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Question: what is the difference between acentric fragments and dicentric fragments
Acentric fragments are chromosome fragments that lack a centromere, the region of the chromosome where the spindle fibers attach during cell division. This means they cannot be properly segregated during cell division and are often lost or degraded. Dicentric fragments, on the other hand, have two centromeres and are pulled in opposite directions during cell division, resulting in DNA damage and potentially chromosomal rearrangements. Both acentric and dicentric fragments are examples of chromosomal aberrations that can lead to genetic disorders and cancer.
March 21, 2023, 2:03 p.m.
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