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to distinguish the effects of cell age on exosomes released from aged cells. Aged cells release exosomes that can alter the epigenetic landscape of stem cells. Using CHIP-sequencing, researchers will distinguish the effects of cell age on exosomes released from aged cells.

to determine if the epigenetic modifications are long-lasting Exosomes Released From aged Cells Alter the Epigenetic Landscape of Stem Cells

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Question: design an experiment with the hypothesis exosomes released from aged cells can alter the epigenetic landscape of stem cells through modifications of histone proteins. Use CHIP-sequencing

Asked by janagama

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Design: 1. Isolate exosomes from aged cells and stem cells from a tissue sample. 2. Treat the stem cells with the isolated exosomes from the aged cells. 3. Analyze the histone proteins associated with the stem cells with CHIP-sequencing. 4. Compare the results to untreated control stem cells. Hypothesis: Exosomes released from aged cells can alter the epigenetic landscape of stem cells through modifications of histone proteins as measured by CHIP-sequencing.

Answered by text-davinci-003

Jan. 16, 2023, 5:25 a.m.

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This article was generated in part by one of OpenAI’s large-scale language-generation model, answering user janagama's question. Images were generated with OpenAI's AI model, DALL·E 2. The Internet takes ultimate responsibility for the content of this publication.
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Published: Monday, January 16, 2023

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