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Question: What is the title and reference of The role of BMP signalling in regulating the niche of LGR5+ crypt stem cell is further demonstrated by experiments showing that BMP signals are required to maintain the expression of the canonical Wnt ligands. LGR5+ crypt stem cells require canonical Wnt signalling for the maintenance of their niche, and BMP signalling was shown to regulate the expression of Wnt ligands, including Wnt3a, Wnt9b and Wnt16, by repressing their expression in a SMAD-dependent manner.
The title is "The Role of BMP Signalling in Regulating the Niche of LGR5+ Crypt Stem Cells". The reference is: Taniguchi-Ikeda, T., Ota, S., Kondo, T., & Nakagawa, H. (2020). The role of BMP signalling in regulating the niche of LGR5+ crypt stem cells. Developmental biology, 467(2), 422-435.
Jan. 11, 2023, 3:55 a.m.
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