Ask AI: Evaluate 2 cell-based therapeutic solution to engineer cartilage using research from the last two years

1. Bone Marrow-Derived Mesenchymal Stem Cells (MSCs): The use of MSCs has emerged as a promising cell-based therapeutic solution for cartilage regeneration. MSCs possess strong regenerative potential and can be easily obtained from the bone marrow of patients, making them a promising source of stem cells for cartilage regeneration. In preclinical studies, MSCs have shown efficacy in repairing damaged cartilage lesions while avoiding adverse outcomes such as tumor formation or immune rejection. 2. Chondrocyte-based Therapy: Chondrocyte-based therapy has also been evaluated as a cell-based therapeutic solution to engineer cartilage. The approach involves the isolation and expansion of autologous chondrocytes, followed by transplantation into the damaged cartilage site. This technique has been studied in both animal models and clinical trials with promising results, demonstrating efficacy in reducing pain and improving mobility and function.