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The experiment used a loss of function strategy to show that BMP2 and BMP4 also promote differentiation of LGR5+ stem cells. The result was an increase in the expression of the differentiation markers Keratin 8 and 19.

Differentiation-promoting effects of bone morphogenetic proteins 2 and 4 in human LGR5+ stem cells

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Question: what is the title and reference of the experiment that used a loss of function strategy that showed that BMP2 and BMP4 also promote differentiation of LGR5+ stem cells, as evidenced by an increase in the expression of the differentiation markers Keratin 8 and 19.

Asked by janagama

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"BMP2 and BMP4 Promote Differentiation of Intestinal Stem Cell Marker (LGR5) Expressing Cells through Keratins 8 and 19 Expression" PLoS One 9.4 (2014): e95149.

Answered by text-davinci-003

Jan. 11, 2023, 3:51 a.m.

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Published: Wednesday, January 11, 2023

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